Research Update
Research news and updates from Wake Forest Baptist Health
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Player Athleticism Increases Head Impact Exposure in Youth Football
A study of youth league football players by researchers at Wake Forest School of Medicine found that higher vertical jumping ability and faster times in speed and agility drills were generally associated with higher head impact exposure, especially in games as compared to practices.
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Diet’s Effect on Gut Bacteria Could Play Role in Reducing Alzheimer’s Risk
Following a certain type of diet could affect the gut microbiome in ways that decrease the risk of Alzheimer’s disease.
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Intensive Blood Pressure Control May Slow Age-Related Brain Damage
Intensively controlling a person’s blood pressure was more effective at slowing the accumulation of white matter lesions in the brain than standard treatment of high blood pressure, according to a nationwide study.
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Implanted Muscle Fiber Fragments Could Help Heal Injuries, Treat Urinary Incontinence
Researchers have developed a “point-of-care” processing method to create uniformly sized muscle fiber fragments that could be implanted into tissue to restore function to treat muscle loss due to traumatic injury or congenital defects.
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Research Funding
Research reported on in this publication was supported by the following grants from the National Institutes of Health (NIH):
Player Athleticism Increases Head Impact Exposure in Youth Football: National Institute of Neurological Disorders and Stroke awards R01 NS094410 and R01 NS082453, National Center for Advancing Translational Sciences grant KL2 TR001421 and the Childress Institute for Pediatric Trauma at Wake Forest Baptist Medical Center.
Diet’s Effect on Gut Bacteria Could Play Role in Reducing Alzheimer’s Risk: Grant P30 AG049638 and award R01 AG055122 from the National Institute on Aging, Department of Defense grant W81XWH-18-1-0118, National Center for Advancing Translational Sciences grant UL1 TR001420 and a grant from the Hartman Family Foundation.
Intensive Blood Pressure Control May Slow Age-Related Brain Damage: NIH Systolic Blood Pressure Intervention Trial, which was jointly funded by the National Heart, Lung, and Blood Institute, the National Institute of Diabetes and Digestive and Kidney Diseases, the National Institute on Aging, and the National Institute of Neurological Disorders and Stroke (HHSN268200900040C, HHSN268200900046C, HHSN268200900047C, HHSN268200900048C, and HHSN268200900049C and interagency agreement A-HL-13-002-001), and the following NIH grants: OD023495, TR000439, RR025755, RR024134, TR000003, RR025771, TR000093, RR025752, TR000073, TR001064, TR000050, TR000005, TR000017, TR000105, TR000445, TR000075, TR000002, TR000064, TR000433, GM103337. Additional funding was provided by the Department of Veterans Affairs. Azilsartan and chlorthalidone (combined with azilsartan) were provided by Takeda Pharmaceuticals International Inc.
Implanted Muscle Fiber Fragments Could Help Heal Injuries, Treat Urinary Incontinence: Department of Defense grant W81XWII-08-1-0333, awarded by the Orthopedics Trauma Research Program.